Tag: vitamin C

Optimize Your Testosterone Levels

Posted on by Diogenes II

 

Testosterone is a hormone — not a male or female hormone — but just a hormone, that simply happens to be produced some 20 times more in men’s testes than in women’s ovaries. It is also a steroid hormone, which means that it’s fat-soluble — allowing it to penetrate and enter directly into cells, as opposed to non-steroid hormones — which sit on the outside of cells. Testosterone is also an anabolic steroid, which means it builds things and supplies things (like protein) for muscle building and (collagen) for bone building. It is also a sex hormone — which means it makes people competitive, aggressive and sometimes unreasonably sensitive. In this article, I will discuss the pathway that decreases testosterone, and the ways to optimize this hormone.

Many articles point out the analysis that testosterone is produced — or rather, manufactured — in the testes of men, and ovaries of women, and adrenal glands of both sexes. But this hormone is greatly affected by the conditions of one particular organ — the largest internal organ: i.e., the liver. Low testosterone levels do not simply indicate that you need to increase your testosterone levels — it indicates that there is some type of malfunction somewhere — highly suspectably initiated in the liver.

But how is testosterone created?

Our body metabolizes cholesterol from the food we eat and from the synthesis of cholesteryl ester that the liver produces. Cholesterol makes hormones, including the hormone pregnenolone. Metabolized pregnenolone is turned into Dehydroepiandrosterone (DHEA) and progesterone. DHEA and progesterone are converted into many other hormones, including testosterone. As previously mentioned, testosterone cannot simply be classified as a male hormone because testosterone can and often do turn into estradiol — a form of estrogen (the so called female hormone). In the bone and brain, testosterone is easily converted to estradiol, by the aromatase enzyme. In the central nervous system, it is this estradiol that serves as the most important feedback signal to the hypothalamus. In many animals, it is this estradiol that masculinizes the brain of the male fetus.

Interestingly, testosterone distribution throughout the body appears surprisingly stingy. Most scientific articles you read will say that about 98 percent of testosterone is strongly or weakly bound to proteins, and about 2 percent is free testosterone, ready for immediate use. Unfortunately, much of what they know about the binding up of testosterone by proteins is pure speculation, based off of hypotheses, and not facts. There are many proteins that are responsible for storing and carrying testosterone, the main ones being sex hormone-binding globulin (SHBG), human serum albumin (HSA), and to a lesser extent, corticosteroid-binding globulin (CBG) and orosomucoid. And then we have after these, “free testosterone”. But the “binding up” or distribution of testosterone by protein is greatly influenced by age. If SHBG — which has a strong bind — is being bound to testosterone at a rate of 65 percent, then that person must be somewhere around 65 years old — or young and ill. If the SHBG is 49 percent, then you ought to expect that person to be somewhere around 49 years old! So SHBG percentage increases with age.

In fact, after about age 30, men naturally or unnaturally lose testosterone levels by 1 or 2 percent each year thereafter — so by the time he reaches the age of 60, that man would expect a testosterone loss anywhere from 30 to 60 percent. The increase of SHBG is an indicative sign of increased toxic heavy metals and a decrease in liver function. So protein-binding increase, like that of SHBG, should be an indicator of increased age, or increased disease! Furthermore, when there is increased heavy metals and liver dysfunction, that opens the way for testosterone to turn into estradiol. This explains why so many men experience dramatically increased estrogen levels and lowered testosterone levels after age 50.

And there is that mighty co-relation between cholesterol and testosterone. In fact, cholesterol is the raw material of testosterone; and a defect in cholesterol directly affects testosterone. If your cholesterol numbers are uncomfortably high, then your testosterone numbers may show uncomfortably low. Being that that raw material — cholesterol — is made in the liver, and testosterone is made from cholesterol — alas — a testosterone problem is most likely coming from a liver problem! And if your cholesterol numbers are, conversely, uncomfortably low, then this low may be too low for the necessary production of adequate testosterone.

Low testosterone levels may also be indicative — a sign — that the liver is storing too high amounts of free iron. This is not a good thing. The liver does not like to store high, free iron because, this damages said organ. It may surely prove wise to get [one’s] ferritin levels tested. Any level over 60 is indicative of too much free iron being stored in and dispersed by the liver. This nowadays is a major cause of decreased testosterone levels in both men and women.

Generally speaking, men between the ages of 40 to 60 should seek a total testosterone number of over 500; and optimally, over 650. Premenopausal women should aim for around 35, and postmenopausal, around 30 or higher. Testosterone increase may enhance sex-drive for both men and women. Noteworthy, the most accurate testosterone test results is obtained at around 8 am in the morning.

So to optimize your testosterone levels, consider rejuvenating the liver therefore. An ayurvedic herb called kutki will help do that. It is no coincidence that kutki also reduces high LDL and its cholesterol and that that herb reduces oxidation of LDL and cholesterol. Other herbs that may be helpful for the liver are burdock root and artichoke extract.

There are also other herbs that will optimize testosterone and the liver, namely fenugreek and ashwagandha. It is well known that both fenugreek and ashwagandha indirectly provide the raw nutrients that boost and optimize testosterone levels in both sexes — male and female. Ashwagandha, used short term, increases sperm volume in men, muscle size, bone strength and sleep quality in both sexes — critical assets needed for testosterone optimization. Fenugreek increases libido. Fenugreek may also manage glucose levels in the blood and increase insulin sensitivity. This increased insulin sensitivity works in favor with testosterone production.

And there are minerals that optimize testosterone levels — namely zinc, selenium, boron, and magnesium. For example, zinc prevents the aromatase enzyme that turns testosterone into estrogen from that process,  thereby by default, helping to accelerate testosterone and sperm production in the testes. Magnesium and boron help activate free testosterone. It is important that you obtain the right type of mineral, preferably in the natural food-base form, rather than the synthetic. For zinc, try Nutrigold Zinc Gold, for selenium, try Food Research Selenium E, for boron, try Vibrant Health Super Natural Boron, and for magnesium, try malate, taurate, glycinate and/or citrate.

And there are vitamins that optimize testosterone levels — namely vitamin D, E and K — the fat soluble vitamins. It seems as no surprise that testosterone has an affinity to fat soluble vitamins, since testosterone is a fat-soluble hormone.

Still another supplement to consider in boosting testosterone is a natural form of vitamin C. As I’ve stated, one of the binding proteins of testosterone is, corticosteroid-binding globulin. Corticosteroid is a constituent of the hormone cortisol.  An unbalanced rise in cortisol decreases testosterone production. Taking natural vitamin C reduces that rise in cortisol. There is an herb-berry called amla — very popular in ayurveda — that contains both natural vitamin C, polyphenols, and copper. These nutrients work in synergy to help build back a better liver, intestines, lymphatic system and colon — things that are all needed to optimize one’s testosterone levels.

Then we also cannot forget about the B vitamins. The [stress] hormone ADRENALINE turns [on] cortisone (inactive) into cortisol (active). But the body is suppose to turn cortisol back into cortisone to prevent long term damage, with an enzyme called 11beta-Hydroxysteroid. But for this enzyme to work, we need dietary niacin to turn the [NADP] cycle into ATP — and that’s also why so many men AND women are low on testosterone! The bottom-line here is, we need daily and adequate amount of B vitamins!

And finally, to deal with free, unbound iron building in the liver, try IP-6/Inositol (on an empty stomach) for a few months. Keep in mind that IP-6 chelates not only iron — but also other minerals (and vitamins) like calcium and zinc. So be sure to increase these with food-base supplements, or nutrition.

Though they are becoming increasingly popular, I still cannot recommend either pine pollen or the herb tribulus terrestris for testosterone issues. Pine pollen contains natural testosterone, which may — over time — atrophy the testes, ovaries and other organs from producing testosterone naturally. You do not want to add testosterone to your body — you want to harness and encourage the organs that produce it, to optimize it. Therefore, tribulus terrestris comes with too many side effects, and will not directly optimize or boost your testosterone levels; and is best to avoid, unless you are using it for specific other reasons.

So to optimize your testosterone levels, consider fixing the liver with:

  • Kutki (Burdock root or artichoke extract may work as well)

And, to nutritionally build back the body, try: 

  • Fenugreek
  • Ashwagandha
  • Zinc: Food Research Zinc Complex or Nutrigold Zinc Gold
  • Selenium: Food Research Selenium E ***
  • Boron: Vibrant Health Super Natural Boron
  • Magnesium: DaVinci Laboratories TRI-MAG 300
  • Vitamin D: Nutrigold K2+D3 Gold ***
  • Vitamin C: Amla
  • Vitamin B: Nutrigold B Complex Gold or FOOD RESEARCH B Stress Complex
  • IP-6/Inositol
  • ***Vitamin E: see above – Food Research Selenium E 
  • ***Vitamin K2: see above – Nutrigold K2+D3 Gold

Can’t Sleep? Try These!

Posted on by Diogenes II

 

The liver is most active at night, at which time, it holds more blood than any other organ of the body! The human body typically needs 8 hours of sleep in complete darkness. For a relatively healthy adult, 6 hours may be sufficient! Melatonin (which is a hormone that gets you to sleep) is produced from your body’s serotonin accumulation. Serotonin starts its conversion into melatonin between the hours of 9:30 p.m. and 10 p.m. And it continues throughout till about 2 a.m. The best hours of sleep are between the hours of 10 p.m. and 6 a.m.

We (all) actually should be sleeping around 6 to 8 hours per night — especially between the hours of 10 p.m and 2 a.m; when the liver is recycling old cells and other toxins. 12 a.m being the end of deep sleep, it is imperative to be sleeping well before this time to receive the full health benefits of deep sleep before midnight. Just like around 11a.m to 1 p.m are the best time period to eat lunch, being digestive enzymes are most active at these times due to solar activity and influences, so is sleep necessary especially around 11 p.m and 1 a.m to destroy old, damaged cells in the body, in a process known as autophagy. The body disposes about 30 to 60 billion cells each day (don’t worry, we have up to 100 trillion more). If these cells are not destroyed, but instead live on, they can become cancerous. Sleep and darkness with melatonin are needed for this process. This is why sleep is so important.

As a quick-fix for insomnia, I have personally discovered and recommend taking 5-HTP (made from Griffonia simplicifolia extract) for a deep, restful sleep. This herb increases a more absorbable form of the neurotransmitter, serotonin, in the brain, supposedly causing a decrease in depression. It will jumpstart your body with more natural melatonin — since metabolized serotonin inevitably turns into melatonin. Take this supplement with your last meal of the day. You are preparing your body for a long fast each time you go to sleep, so avoid eating a large meal 4 hours or more beforehand of sleeping. 5-HTP should be used sparingly and only temporarily. It should not be used with other neurological drugs.

Another herb that is very effective at calming the nerves and increasing the ability to sleep restfully is called blue vervain. While adrenaline keeps us up — or wakes us up — blue vervain works on the parasympathetic nervous system, that makes us relax.  It can be consumed multiple ways: as tea, tincture, cream or capsule. My personal preference is to use it as a non-alcoholic tincture one hour before bed. Pregnant women, breastfeeding mothers, the “anemic” and those on blood thinners should avoid this herb however.

Another sleep-aid supplement would be quality, organic reishi mushrooms of the Ganoderma lingzhi species (not the G. lucidum species). This is the species used in Asia, and is of better quality to the European G. Lucidum species. Also be cautious of taking this mushroom if you are on any medication, especially for low blood pressure, diabetes or any autoimmune disorder. Rare symptoms of dry mouth, headaches, rash and stomach issues have occasionally been reported. Pregnant women, also, should avoid this mushroom. Most products sold of this mushroom are not authentic and is of low quality — so be sure to do your research.

Another more practical and efficient way to effect sleep is by consuming an absorbable form of magnesium a few hours before bedtime, such as glycinate or taurate. This mineral is not only effective at making you sleep, but it also balances all other hormonal networks needed for sleep, while also reducing symptoms of depression. In those who are deficient, it lowers blood pressure and relaxes the muscles, thus enabling more effective and restful sleep.

What too is most likely lacking in the case of insomnia or restless sleep is your body’s reserve of natural vitamin C. Our adrenal glands need and store more vitamin C than any other part of the body. They use it to regulate cortisol and other hormones. When you lack vitamin C, cortisol is increased, causing an imbalance between melatonin (produced by the pineal gland in the brain, the retina of the eyes and other places) and cortisol. Cortisol is actually competing with melatonin for space, thus reducing melatonin’s complete metabolism. Like magnesium, vitamin C is also effective at balancing neurology and depression. Sources of natural vitamin C include amla berries and acerola berries, which can be purchased in supplement form. Oranges and red peppers have traditionally been thought of as good sources of natural vitamin C as well.

To improve your sleep, also keep away from the television or other such devices for at least two hours before bed. The number one cause of stress and increase in cortisol is actually watching too much tv, via television, tablet or phone. Our subconscious mind actually counts all those thousands of images coming into our eyes every second.

It should be obvious to note that if you have a sleeping problem, that you should avoid stimulants like caffeine at all cost. Avoid coffee at least 10 hours before sleep!

If you wake up at night to urinate, that means that your insulin level may be high. Reduce sugar. It also means your adrenaline is high. That is why folks often find themselves waking up at 2:30 a.m — when night-time adrenaline peaks — and not be able to get back to sleep. Avoiding drinking anything close to bedtime would help. That herb blue vervain will also calm your nerves, thus pacifying your production of adrenaline.

So in summary, the common denominator with insomnia appears to be an underlying state of depression. To effect more restful and timely night sleep, try:

  • 5-HTP (100 mg) temporarily, as a quick fix
  • Blue vervain, which will effectively help you sleep
  • Authentic, organic reishi mushroom (of the Ganoderma lingzhi species)
  • An absorbable form of magnesium (400 mg)
  • Natural vitamin C, e.g., amla, acerola, or camu camu
  • (Avoid) electronic devices at least two hours before bedtime
  • (Avoid) caffeine hours before bedtime.
  • (Avoid) drinking before bedtime to avoid waking up to urinate.

Overcoming Hypothyroidism & Hashimoto’s

Posted on by Diogenes II

 

Hypothyroidism is an under-active thyroid condition, resulting in the thyroid gland not producing or converting enough thyroid hormones. This results in familiar and characteristic symptoms, often striking older women. The condition is said to be autoimmune if it is not resolved by iodine or selenium or any other mineral sufficiency, or if these mineral-increase causes swelling and further irritation on the thyroid. The supposed autoimmune condition of hypothyroidism is known as Hashimoto’s thyroiditis. Most hypothyroidism is elevated to the level of Hashimoto’s (9:1). Here we will discuss what is  believed to be the true cause of this and that condition, and the protocol needed to correct it, including supporting the liver, kidneys, lymphatic  system and adrenal glands,  while also supplementing on critical nutrients that had consequently been depleted.

We have hypothyroidism and/or Hashimoto’s also because we are internally inflamed and clogged with undigested protein in the vessel walls of our capillaries. Our lymphatic system becomes clogged by this build up of excess proteins — polluting the blood and affecting the sensitive thyroid. An ayurvedic herb however called manjistha will help unclog it — thus assisting and allowing proper thyroid function again. This is truly great news!

When antibodies attack the thyroid, then hypothyroidism is now officially called an autoimmune disease — Hashimoto’s.  Hashimoto’s indeed should not be labeled as an auto-immune disorder, as is widely accepted — but more accurately as an adrenal dysfunction. The thyroid makes only two TRUE hormones, while the adrenals make at least 50. The adrenal glands are in control of the immune system. If there is something wrong with your immune system, then there is something wrong with your adrenal glands. The adrenal glands consist not only of the two things on top of your kidneys — it consists of your entire skin structure. Your skin cells ARE your adrenals!

If you have developed hypothyroidism or Hashimoto’s, you surely are low on vitamin A, a.k.a. retinol. This is a vitamin that is adequately stored in a proper functioning liver,  and acts as a hormone. Thus a vitamin A deficiency may indicate liver dysfunction. This vitamin A is carried by a transport protein called transthyretin (TTR). This protein also carries T4 — the near inactive hormone made by the thyroid — a.k.a. thyroxine. If there is no vitamin A (retinol), then there may be also low or no proper T4 transportation, either from TTR damage or nutrient deficiency. Then there may be no bio-available conversion of T4 to the very active T3! To improve bio-available retinol in the blood, we need it from our diet. Grass-fed butter and grass-fed/grass-finished liver will actualize this process. So will a fruit like persimmon. Carrot(s) because of its beta carotene content, which converts to a smaller percentage of retinol in the body, is another option. So will sweet potato, and malabar, a.k.a. saan choy (an oriental leafy green). Our adrenals also love retinol.

And what else does our adrenals like? Natural vitamin C — lots of it. Natural vitamin C also has a transport protein, called tyrosinase, which carries numerous molecules of bio-available copper. If you want to feed your adrenals, then give them amla or acerola berry: all sources of natural vitamin C.

Another best thing that our adrenals like is the natural B vitamins. Bee pollen contains all the natural B vitamins your adrenals need, especial vitamin B5, which your adrenals really love. (Taste-test to make sure you’re not allergic to it though.) Bee pollen also contains bio-available copper.

Contrary to popular belief, we do not need as much vitamin D as you may think. 60-80 ng/ml of vitamin D is actually too much. Too much vitamin D creates massive amounts of hydrogen peroxide. Though hydrogen peroxide is a free radical that is needed to a certain degree, too much of it will damage your cells. A vitamin D level of 32 to 45 nanograms per milliliter is actually ideal

In dealing with inflammation, the internal body loses one mineral faster than any other — even by something as simple as stress — yet that mineral is arguably the most important: that mineral is called magnesium. When magnesium leaves, it takes other minerals like potassium and copper with it. Magnesium is like the glue that keeps all the other minerals in place and together. A loss of magnesium will eventually create an inferno of inflammation throughout the body. Not only do you need to replace magnesium daily — it must also be absorbable. If magnesium oxide or magnesium carbonate comes to mind when you think about replacing magnesium, you are sadly mistaken. The absorption rate of these forms of magnesium is pathetically low: 4% or less. Consider instead magnesium glycinate/malate/taurate/citrate.

Vitamin B6, in the form of P5P, further increases magnesium absorption throughout the body on a cellular level. So does healthier salts, namely, Kosher salt (Diamond crystal) or Pickling salt.

If there is inflammation anywhere in the body, there is almost always an ample supply of iron — but not just any iron: destructive, unbound iron, rusting the targeted tissue area. If iron is not attached to hemoglobin or whatever else it should be attached to, it roams freely, causing chaos and inflammation. The thyroid appears to be one of unbound iron’s favorite target. To reduce hypothyroidism\Hashimoto’s, a protocol to reduce this form of iron must be implemented. Consuming the vitamins and other supplements previously mentioned, in their natural form, would be a way to turn unbound iron back into useful iron, your body can absorb properly. Another way is to take IP-6 on an empty stomach, away from food and other supplements. IP-6 is known to chelate iron, along with zinc and calcium out of the body. So naturally, you would want to consume foods with more zinc and calcium during this process.

If you have the condition listed in this article, you may consider stop taking medications, and consider the natural route. Medication has a tendency to make things feel better temporarily, while making thing worse permanently. As a start, consider:

  • A quality brand iodine supplement, like Icelandic Sea Kelp, or a natural selenium supplement like Food Research Selenium E, and note if the condition was caused by any of these popular mineral deficiencies. Otherwise, add:

Healing herbs:

  • Kutki, guduchi and/or burdock root for the liver
  • Astragalus and dandelion root for the kidneys
  • Manjistha for the lymphatic system

Nutritional Support:

  • Grassfed butter/liver: (liver should be no more than one ounce per day, or 7 ounces per week.)
  • Persimmons, carrots (not too much though), sweet potato (not too much though), malabar a.k.a. saan choy (not too much though): all of these contain high beta carotene which can convert to retinol.
  • Natural vitamin C (amla, acerola berry)
  • Bee pollen
  • Magnesium (glycinate, malate, citrate, taurate)
  • P5P

Reducing Excess, Unbound Iron:

  • IP-6 on an empty stomach

(Note: IP-6 depletes certain other minerals, like zinc. So be sure to increase sources of this and other minerals and vitamins.)